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The Science

The biology behind weight management

A mechanism-first comparison of the hormones and pathways that shape appetite and metabolism.

PathwayMechanismPrimary Role
GLP-1Released after eating; signals fullness and supports glucose-dependent insulin secretion.Appetite & satiety
GIPAn incretin hormone studied alongside GLP-1 for complementary metabolic effects.Glucose metabolism
GlucagonAssociated with energy expenditure in research models.Energy expenditure
GhrelinThe 'hunger hormone' that rises before meals.Hunger signalling
LeptinSignals energy sufficiency and satiety from fat stores.Long-term balance

This comparison focuses on biological mechanisms rather than outcomes. It is educational only and is not medical advice.

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